Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 AlteredExpression disease BEFREE TIPE2 mRNA was associated with various stages of chronic HBV infection, ranging from CHB to liver cirrhosis and HCC. 31661000 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 Biomarker disease BEFREE Treatment with TIPE‑2 markedly suppressed HCC cell proliferation and increased the number of cells in S phase of the cell cycle. 29568863 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 Biomarker disease BEFREE Previous studies revealed that TIPE2 inhibits hepatocellular carcinoma metastasis by repressing Ral and Rac1 GTPases. 26530498 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 Biomarker disease BEFREE Recently, TIPE2 has been shown to inhibit hepatocarcinoma growth and metastasis through targeting Ras and Rac1. 26987289 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 AlteredExpression disease BEFREE Our results demonstrated that the expression of TIPE2 was significantly reduced in HCC tissues compared to that in the paracarcinoma tissues. 27696294 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 Biomarker disease BEFREE Taken together, these findings demonstrate that TIPE2 was able to suppress TNF-α-induced hepatocellular carcinoma metastasis by inhibiting Erk1/2 and NF-κB activation, indicating that both TNF-α and TIPE2 might be potential targets for the treatment of HCC metastasis. 25339267 2015