NANOG, Nanog homeobox, 79923

N. diseases: 140; N. variants: 3
Disease: Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.030 AlteredExpression disease BEFREE Genetic probes showed that mouse GBM-derived CTC exhibited Sox2/ETn transcriptional activation and expressed glioma CSC markers, consistent with robust expression of stemness-associated genes including SOX2, OCT4, and NANOG in human GBM patient-derived samples containing CTC. 30322863 2018
CUI: C0017638
Disease: Glioma
Glioma 		0.030 Biomarker disease BEFREE Moreover, BIX01294 enhanced the cytotoxic effect of TMZ on glioma stem-like cells, although it was not associated with modulation of the pluripotency markers (<i>NANOG, SOX2, CD133</i>) expression or methylation of <i>NANOG</i> and <i>SOX2</i> gene promoters. 30450051 2018
CUI: C0017638
Disease: Glioma
Glioma 		0.030 Biomarker disease BEFREE NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53. 20581802 2010