|
Liver Cirrhosis, Experimental
|
0.300 |
Biomarker
|
disease |
CTD_human |
Systems level analysis and identification of pathways and networks associated with liver fibrosis.
|
25380136 |
2014 |
|
Neoplasms
|
0.030 |
AlteredExpression
|
group |
BEFREE |
We wanted to assess the expression of CARPs VIII and XI in these tumors and study their association to different clinicopathological features and tumor-associated CAs II, IX and XII.
|
29792187 |
2018 |
|
Neoplasms
|
0.030 |
GeneticVariation
|
group |
BEFREE |
CARP is a potential tumor suppressor in gastric carcinoma and a single-nucleotide polymorphism in CARP gene might increase the risk of gastric carcinoma.
|
24870804 |
2014 |
|
Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
Together, these results indicated that C10ORF97 functions as a novel tumor suppressor by modulating several key G(1)/S-regulatory proteins by interacting with JAB1.
|
21499297 |
2011 |
|
Cardiomyopathy, Dilated
|
0.020 |
Biomarker
|
group |
BEFREE |
MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy.
|
27353086 |
2016 |
|
Cardiomyopathy, Dilated
|
0.020 |
GeneticVariation
|
group |
BEFREE |
Mutations in the ANKRD1 gene encoding CARP are responsible for human dilated cardiomyopathy.
|
19525294 |
2009 |
|
Astrocytoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
There are no reports on CARPs in human astrocytomas or oligodendroglial tumors.
|
29792187 |
2018 |
|
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Furthermore, the molecular mechanisms beneath the cancer promoting qualities of CARPs have not yet been discovered.
|
29792187 |
2018 |
|
oligodendroglioma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In WHO grade II-IV astrocytomas, CARPs were associated with molecular events related to more benign behavior, which was the case with CARP VIII in oligodendrogliomas and oligoastrocytomas as well.
|
29792187 |
2018 |
|
Carcinogenesis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Thus, more studies concerning role of CARPs in oncogenesis are needed.
|
29792187 |
2018 |
|
Well Differentiated Oligodendroglioma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In WHO grade II-IV astrocytomas, CARPs were associated with molecular events related to more benign behavior, which was the case with CARP VIII in oligodendrogliomas and oligoastrocytomas as well.
|
29792187 |
2018 |
|
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
Furthermore, the molecular mechanisms beneath the cancer promoting qualities of CARPs have not yet been discovered.
|
29792187 |
2018 |
|
Cerebrovascular accident
|
0.010 |
Biomarker
|
group |
BEFREE |
Cationic arginine-rich and poly-arginine peptides (referred to as CARPs) have potent neuroprotective properties in in vitro excitotoxicity and in vivo models of stroke.
|
29177102 |
2017 |
|
Stomach Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
It displayed that the TT genotype of rs2297882 in the CARP gene was associated with an increased risk of gastric carcinoma.
|
24870804 |
2014 |
|
Ataxia
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish.
|
23087022 |
2013 |
|
Cerebellar Ataxia
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish.
|
23087022 |
2013 |
|
Mental Retardation
|
0.010 |
Biomarker
|
disease |
BEFREE |
This work reveals an evolutionarily conserved function of CARP VIII in brain development and introduces a novel zebrafish model in which to investigate the mechanisms of CARP VIII-related ataxia and mental retardation in humans.
|
23087022 |
2013 |
|
Intellectual Disability
|
0.010 |
Biomarker
|
group |
BEFREE |
This work reveals an evolutionarily conserved function of CARP VIII in brain development and introduces a novel zebrafish model in which to investigate the mechanisms of CARP VIII-related ataxia and mental retardation in humans.
|
23087022 |
2013 |
|
Non-Small Cell Lung Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
These findings led us to hypothesize that a single-nucleotide polymorphism (SNP) in the C10ORF97 gene that affects its expression might be associated with susceptibility to NSCLC.
|
21499297 |
2011 |
|
Inflammatory Bowel Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Caspase recruitment domain (CARD)-containing protein 8 (CARD8) is a potential candidate risk gene for inflammatory bowel disease (IBD) because of its role as a component of the NALP3 inflammasome and as an inhibitor of nuclear factor-kappa B.
|
21248762 |
2011 |
|
Carcinoma of lung
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In an earlier study we showed that C10ORF97 (chromosome-10, open reading frame-97) was expressed in almost all of the tissues and cell lines tested, and that it inhibited the growth of seven tumor cell lines, including two lung carcinoma cell lines (A549 and PG).
|
21499297 |
2011 |
|
Hypertrophic Cardiomyopathy
|
0.010 |
Biomarker
|
disease |
BEFREE |
CARP abnormalities may be involved in the pathogenesis of HCM.
|
19608031 |
2009 |
|
Cardiomyopathy, Familial Idiopathic
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
On the basis of genetic and functional analysis of CARP mutations, we have identified ANKRD1 as a new gene associated with DCM, accounting for approximately 2% of cases.
|
19525294 |
2009 |
|
Rhabdomyosarcoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In this study, we comparatively analyzed expression of Arpp and Carp protein in skeletal and cardiac muscles and rhabdomyosarcomas (RMSs).
|
12000728 |
2002 |
|
Breast adenocarcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Congener- and concentration-dependent antagonism of 17beta-estradiol (E2)-induced gene expression, rather than induction of ER-dependent gene expression, was observed for the MeSO(2)-PCBs on lucifierase activity in stably transfected human breast adenocarcinoma T47D cells (ER-CALUX) and vitellogenin (vtg) production in primary hepatocytes from male carp fish (Cyprinus carpio) (CARP-HEP/vtg).
|
12377985 |
2002 |