|
Lung Neoplasms
|
0.310 |
Biomarker
|
group |
BEFREE |
Moreover, siPLK1-CPP33-CLP exhibits prolonged blood circulation, enhanced tumor accumulation, effective suppression of tumor growth, and considerably elevated survival time of orthotopic A549 human lung tumor-bearing nude mice.
|
31231966 |
2019 |
|
Lung Neoplasms
|
0.310 |
Biomarker
|
group |
CTD_human |
Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents.
|
27935865 |
2017 |
|
Malignant neoplasm of lung
|
0.300 |
Biomarker
|
disease |
CTD_human |
Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents.
|
27935865 |
2017 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Cultured human pulmonary epithelial cell line A549 was challenged with LPS to induce cell injury, and CLP mouse model was generated to mimic clinical condition of systemic sepsis.
|
30918470 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Mice in sepsis were administered CLP surgery.
|
30690081 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Lactobacillus rhamnosus GG Ameliorates Liver Injury and Hypoxic Hepatitis in Rat Model of CLP-Induced Sepsis.
|
31049763 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Sepsis and AKI were induced 12 h after CLP.
|
31223614 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Additionally, the decreased levels of FRAP and GSH induced by sepsis were remarkably (p < 0.05) risen by the administration of DDWs and ML in comparison to the CLP group.
|
30961427 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Furthermore, PRAK dysfunction could lead to impaired NET-mediated antibacterial activity and shorten the survival of mice with CLP-induced sepsis.
|
31231384 |
2019 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
The purpose of this study was to conduct a 3-dimensional assessment of possible dental crown asymmetry in dental crown shape and/or size that was not clinically visible in unilateral cleft lip and palate (UCLP) patients on the maxilla and mandible and make a comparison to the control group without CLP.
|
31215763 |
2019 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Oral cleft was classified in the following group: cleft lip only - CLO (complete or incomplete, unilateral or bilateral); complete cleft lip and palate - CLP (unilateral or bilateral); and, cleft palate only - CPO (complete or incomplete).
|
31226652 |
2019 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
One hundred thirty primary CL repairs (isolated CL = 59; cleft lip and palate [CLP] = 71) and 140 primary CP repairs (isolated CP = 72; CLP = 69): At the first postoperative visit, 21.54% of CL and 57.14% of CP repair patients had not returned to their immediate preoperative weights ( P < .0001).
|
29742363 |
2019 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Furthermore, PRAK dysfunction could lead to impaired NET-mediated antibacterial activity and shorten the survival of mice with CLP-induced sepsis.
|
31231384 |
2019 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Mice in sepsis were administered CLP surgery.
|
30690081 |
2019 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Sepsis and AKI were induced 12 h after CLP.
|
31223614 |
2019 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Additionally, the decreased levels of FRAP and GSH induced by sepsis were remarkably (p < 0.05) risen by the administration of DDWs and ML in comparison to the CLP group.
|
30961427 |
2019 |
|
Sepsis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Lactobacillus rhamnosus GG Ameliorates Liver Injury and Hypoxic Hepatitis in Rat Model of CLP-Induced Sepsis.
|
31049763 |
2019 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
In addition, survival of wild type mice subjected to the lethal CLP sepsis was not improved with broad-spectrum antibiotics, whereas the survival of NFATc3 deficient mice was improved to 40-60% when treated with imipenem.
|
29535830 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Inhibition of matrix metalloproteinase 8 and tumor necrosis factor receptor 1 might have therapeutic potential to treat sepsis and proof-of-principle was provided as therapeutics that inhibit both tumor necrosis factor receptor 1 and matrix metalloproteinase 8 are effective in CLP.
|
29095202 |
2018 |
|
Septicemia
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
In mice with cecal ligation and puncture-induced sepsis, treatment with GRK2 inhibitor reduced high levels of oxidative and nitrosative stress in the mice brains, where GRK2 expression was up-regulated, alleviated neurohistological damage observed in cerebral cortex sections, and conferred a significant survival advantage to CLP mice.
|
29500815 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
These results suggested that the cecal ligation combined with puncture drainage model of sepsis is more stable than that of the simple cecal ligation and puncture model of sepsis in the rat, which resolved the problem of puncture wrapped in the traditional CLP model of sepsis in rat.
|
29937001 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
By combining phenotypic analysis of exhaustion markers with functional analysis of cytokine production, we found that PD-1+ CD4+ cells in cancer hosts failed to make any cytokines following CLP, while the 2B4+ PD-1lo cells in cancer mice secreted increased TNF during sepsis.
|
29338031 |
2018 |
|
Septicemia
|
0.100 |
Biomarker
|
disease |
BEFREE |
Polymicrobial sepsis (after cecal ligation and puncture, CLP) causes robust complement activation with release of C5a.
|
29914696 |
2018 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Subjects were grouped on the basis of postnatal diagnosis: (1) RS (micrognathia, glossoptosis, airway obstruction), (2) micrognathia without airway obstruction ("micrognathia"), (3) cleft lip and palate ("CLP"), and (4) gestational age-matched controls.
|
29460382 |
2018 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Inclusion criteria were 1) prenatal MRI of adequate quality, 2) liveborn infant, and 3) postnatal diagnosis of RS (Robin group) or cleft lip and palate (CLP group).
|
29125932 |
2018 |