|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
The purpose of this study was to conduct a 3-dimensional assessment of possible dental crown asymmetry in dental crown shape and/or size that was not clinically visible in unilateral cleft lip and palate (UCLP) patients on the maxilla and mandible and make a comparison to the control group without CLP.
|
31215763 |
2019 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Oral cleft was classified in the following group: cleft lip only - CLO (complete or incomplete, unilateral or bilateral); complete cleft lip and palate - CLP (unilateral or bilateral); and, cleft palate only - CPO (complete or incomplete).
|
31226652 |
2019 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
One hundred thirty primary CL repairs (isolated CL = 59; cleft lip and palate [CLP] = 71) and 140 primary CP repairs (isolated CP = 72; CLP = 69): At the first postoperative visit, 21.54% of CL and 57.14% of CP repair patients had not returned to their immediate preoperative weights ( P < .0001).
|
29742363 |
2019 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Subjects were grouped on the basis of postnatal diagnosis: (1) RS (micrognathia, glossoptosis, airway obstruction), (2) micrognathia without airway obstruction ("micrognathia"), (3) cleft lip and palate ("CLP"), and (4) gestational age-matched controls.
|
29460382 |
2018 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Inclusion criteria were 1) prenatal MRI of adequate quality, 2) liveborn infant, and 3) postnatal diagnosis of RS (Robin group) or cleft lip and palate (CLP group).
|
29125932 |
2018 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We assessed the formation of the oral microbiota in infants with complete cleft lip and palate (CLP <i>n</i> = 30) or cleft soft palate (CSP <i>n</i> = 25) in the neonatal period (T1 time) and again in the gum pad stage (T2 time).
|
28393073 |
2017 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These data provide the first mechanistic insight into the heightened caries susceptibility associated with CLP and indicate a direct role for the major CLP gene Irf6 in salivary gland development and a significant role in regulating oral immunity.
|
27927890 |
2017 |
|
Cleft palate with cleft lip
|
0.100 |
Biomarker
|
disease |
BEFREE |
Combining the results of chromosomal linkage studies of unidentified human CLP genes with insights from the mouse models, the following previously unexamined genes are identified as strong candidate genes for causative roles in human nonsyndromic CLP: BMP4, BMPR1B, TFAP2A, SOX4, WNT9B, WNT3, and SP8.
|
18181213 |
2008 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
There were 17 males and 16 females of Caucasian origin, ranging from 3 to 18 years (15 with cleft lip and palate [CLP], 10 with cleft lip [CL], and 8 with cleft palate [CP]), collected from five craniofacial centers (United States and Canada).
|
15516164 |
2004 |
|
Cleft palate with cleft lip
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The identification of a genetic locus associated with this disease would be an important advance in CLP genetic counselling and lead to a better understanding of the genetic basis of CLP.
|
9081766 |
1996 |