Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233794
Disease: Memory impairment
Memory impairment
0.030 Biomarker phenotype BEFREE However, there is no direct evidence that ANP32A can induce neurodegeneration and memory deficits. 29782322 2018
CUI: C0233794
Disease: Memory impairment
Memory impairment
0.030 Biomarker phenotype BEFREE Here we investigated whether downregulating ANP32A can rescue AD-like synapse and memory deficits. 28472990 2017
CUI: C0233794
Disease: Memory impairment
Memory impairment
0.030 AlteredExpression phenotype BEFREE The I1PP2A rats showed a decrease in brain protein phosphatase-2A activity, abnormal hyperphosphorylation of tau, neurodegeneration, an increase in the level of activated glycogen synthase kinase-3beta, enhanced expression of intraneuronal amyloid-beta and spatial reference memory deficit; littermates treated identically but with vector only, i.e., adeno-associated virus vector-1-enhanced GFP, served as a control. 26697860 2015