Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.510 Biomarker disease PSYGENET We found that a single nucleotide polymorphism in the CAMK4 promoter was significantly associated with cocaine addiction, whereas variations in the CREB promoter regions did not correlate with drug abuse. 19001277 2008
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.510 Biomarker disease CTD_human We found that a single nucleotide polymorphism in the CAMK4 promoter was significantly associated with cocaine addiction, whereas variations in the CREB promoter regions did not correlate with drug abuse. 19001277 2008
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.510 GeneticVariation disease BEFREE We found that a single nucleotide polymorphism in the CAMK4 promoter was significantly associated with cocaine addiction, whereas variations in the CREB promoter regions did not correlate with drug abuse. 19001277 2008
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic 		0.310 GeneticVariation disease BEFREE The purpose of the present study is to compare the frequency of CAMKIV genotypes and alleles between AD and control subjects in Korea. 28734942 2017
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.300 Biomarker disease CTD_human Loss of the Ca2+/calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine. 19001277 2008
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders 		0.300 Biomarker group CTD_human Loss of the Ca2+/calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine. 19001277 2008
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		0.300 GeneticVariation disease UNIPROT
CUI: C0345958
Disease: Large cell carcinoma of lung
Large cell carcinoma of lung 		0.300 GeneticVariation disease UNIPROT
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.150 GeneticVariation group GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.150 Biomarker group BEFREE CaMKIV has been extensively studied in autoimmune diseases, but a role in idiopathic intestinal inflammation has not been described. 30113881 2019
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.150 Biomarker group BEFREE In lupus-prone mice, targeted delivery of a CaMK4 inhibitor to CD4<sup>+</sup> T cells suppresses both autoimmunity and the development of nephritis. 30333818 2018
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.150 Biomarker group BEFREE Although accumulating evidence indicates that CaMK4 plays important roles in the immune responses, the precise molecular mechanisms underlying the development of autoimmune diseases and inflammatory disorders have not been established. 29252071 2018
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.150 Biomarker group BEFREE Collectively, our results suggest that CaMK4 inhibition has potential as a therapeutic strategy for Th17-driven autoimmune diseases. 24667640 2014
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.150 Biomarker group BEFREE Suppression of autoimmunity and organ pathology in lupus-prone mice upon inhibition of calcium/calmodulin-dependent protein kinase type IV. 20954187 2011
CUI: C0004096
Disease: Asthma
Asthma 		0.100 GeneticVariation disease GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474 2019
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism 		0.100 GeneticVariation disease GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C1314691
Disease: Age at menarche
Age at menarche 		0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C3150797
Disease: AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 6
AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 6 		0.100 GeneticVariation disease GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C4014795
Disease: AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1 		0.100 GeneticVariation disease GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C4310768
Disease: AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2 		0.100 GeneticVariation disease GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0596887
Disease: mathematical ability
mathematical ability 		0.100 GeneticVariation phenotype GWASCAT Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. 30038396 2018
CUI: C0007758
Disease: Cerebellar Ataxia
Cerebellar Ataxia 		0.100 GeneticVariation phenotype CLINVAR
CUI: C0013362
Disease: Dysarthria
Dysarthria 		0.100 GeneticVariation disease CLINVAR
CUI: C0013421
Disease: Dystonia
Dystonia 		0.100 GeneticVariation phenotype CLINVAR
CUI: C0233514
Disease: Abnormal behavior
Abnormal behavior 		0.100 GeneticVariation phenotype CLINVAR