DisGeNET - a database of gene-disease associations

MAP1LC3B, microtubule associated protein 1 light chain 3 beta, 81631

N. diseases: 167; N. variants: 1

Disease: Renal Cell Carcinoma ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.020

AlteredExpression

disease

BEFREE

Also, increases in LC3B and p62 expression suggest a blockage of the autophagic flux in RCC in response to 10b.

31260889

2019

CUI:	C0007134
Disease:	Renal Cell Carcinoma

Renal Cell Carcinoma

0.020

Biomarker

disease

BEFREE

Ubiquitination of MAP1LC3B by pVHL is associated with autophagy and cell death in renal cell carcinoma.

30902965

2019