TKTL1, transketolase like 1, 8277

N. diseases: 76; N. variants: 6
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE These findings unveil a unrecognized interaction between the invasion-related uPAR and IL-TKRs in the control of glycolysis and disclose a new pharmacological target (i.e., uPAR/IL-TKRs axis) for the therapy of melanoma. 28577299 2017
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE The present study evaluates the role of TKTL1 as a mediator of disease progression in melanoma associated with a defective methylation phenotype. 26907172 2016
CUI: C0025202
Disease: melanoma
melanoma 		0.030 AlteredExpression disease BEFREE We identified increased TKTL1 protein levels in malignant conjunctival tumors compared with control samples and detected an average IRS of 1.78 (standard deviation [SD], ± 0.46) for melanomas, 1.3 for lymphomas (SD, ± 0.79), and 1.22 for squamous cell carcinomas (SD, ± 0. 22658715 2012