BAP1, BRCA1 associated protein 1, 8314

N. diseases: 299; N. variants: 72
Disease: Well-differentiated papillary mesothelioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1337012
Disease: Well-differentiated papillary mesothelioma
Well-differentiated papillary mesothelioma 		0.040 AlteredExpression disease BEFREE Immunohistochemistry demonstrated intact BAP1 expression in all cases of well-differentiated papillary mesothelioma, indicating that this is a reliable marker for distinguishing well-differentiated papillary mesothelioma from malignant mesotheliomas that frequently display loss of expression. 30171198 2019
CUI: C1337012
Disease: Well-differentiated papillary mesothelioma
Well-differentiated papillary mesothelioma 		0.040 Biomarker disease BEFREE All 3 cases showed BAP1 loss in both WDPM and the matched MM. 29763720 2018
CUI: C1337012
Disease: Well-differentiated papillary mesothelioma
Well-differentiated papillary mesothelioma 		0.040 AlteredExpression disease BEFREE The expression of BAP1 and EZH2 was investigated by immunohistochemistry in 32 malignant mesotheliomas and 44 benign mesothelial proliferative lesions, including well-differentiated papillary mesothelioma (n = 4), mesothelial inclusion cyst (n = 22), and reactive mesothelial hyperplasia (n = 18). 27859460 2017
CUI: C1337012
Disease: Well-differentiated papillary mesothelioma
Well-differentiated papillary mesothelioma 		0.040 GeneticVariation disease BEFREE To our knowledge, this is the first description of WDPM in two siblings who also presented with a germline BAP1 mutation. 23585512 2013