CASP1, caspase 1, 834

N. diseases: 444; N. variants: 5
Disease: Pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030193
Disease: Pain
Pain 		0.230 AlteredExpression phenotype BEFREE Prolonged postsurgical pain was associated with increased expression of inflammatory genes, including those encoding Toll-like receptor 4, NOD like receptor protein 3 (NLRP3), nuclear factor kappa B (NFκB), caspase-1, interleukin-1β, and tumor necrosis factor (P < .05). 29596097 2019
CUI: C0030193
Disease: Pain
Pain 		0.230 Biomarker phenotype BEFREE A decrease in the ECR pressure pain thresholds was correlated (P < .027) with an increase in the P45 amplitude at a centroparietal recording site. 29803671 2018
CUI: C0030193
Disease: Pain
Pain 		0.230 Biomarker phenotype BEFREE This study suggests that NLRP3 and its downstream product caspase-1 have a limited role in the development of burn-induced pain. 28040362 2017
CUI: C0030193
Disease: Pain
Pain 		0.230 Biomarker phenotype RGD The NALP1 inflammasome controls cytokine production and nociception in a rat fracture model of complex regional pain syndrome. 19853379 2009