CASP3, caspase 3, 836

N. diseases: 819; N. variants: 26
Disease: nervous system disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.320 Biomarker group BEFREE Collectively, JDP2 knockout effectively attenuate TBI in vivo and in vitro through blocking Caspase-3 activation, providing a potential therapeutic target for TBI or even other neurological disorders. 30217453 2018
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.320 Biomarker group BEFREE Our findings reveal a novel role for appoptosin in neurological disorders with tau neuropathology, linking caspase-3-mediated tau cleavage to synaptic dysfunction and behavioral/motor defects. 26335643 2015
CUI: C0027765
Disease: nervous system disorder
nervous system disorder 		0.320 Biomarker group CTD_human Neuronal apoptosis associated with morphine tolerance: evidence for an opioid-induced neurotoxic mechanism. 12196588 2002