CASP3, caspase 3, 836

N. diseases: 819; N. variants: 26
Disease: Skin Carcinogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519346
Disease: Skin Carcinogenesis
Skin Carcinogenesis 		0.020 AlteredExpression disease BEFREE Network analysis also implied that UVA and UVB induce quite different responses, and that UVA results in cell death as well as inflammation mediated by caspase-3 and activator protein 1/nuclear factor kappa-light-chain-enhancer of activated B cells (AP-1/NF-B), while UVB predominantly increases the risk of skin carcinogenesis involved with oncogenes such as p53 and c-Myc. 31756938 2019
CUI: C1519346
Disease: Skin Carcinogenesis
Skin Carcinogenesis 		0.020 AlteredExpression disease BEFREE UV-B or AGRO exposure is able to induce histopathological changes and altered expression of cleaved caspase-3 and Ki-67 in rat skin, thus being categorized as a risk condition for skin carcinogenesis. 31519631 2019