H4C12, H4 clustered histone 12, 8362

N. diseases: 121; N. variants: 1
Disease: Carcinogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 PosttranslationalModification phenotype BEFREE The results suggest that the promoter hypermethylation of HIST1H4K is rather due to aging than related to prostate carcinogenesis. 24065480 2014
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 Biomarker phenotype BEFREE On the basis of these results, we propose that lncRNA-JADE is a key functional link that connects the DDR to histone H4 acetylation, and that dysregulation of lncRNA-JADE may contribute to breast tumorigenesis. 24097061 2013
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 PosttranslationalModification phenotype BEFREE This review presents current evidence of the role of histone H4 lysine 20 methylation in normal and cancer cells and during tumorigenesis induced by genotoxic and nongenotoxic carcinogens. 22035019 2012
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.040 PosttranslationalModification phenotype BEFREE We investigated whether epigenetic changes of histone H4 are involved in lung carcinogenesis. 18974389 2008