H4C8, H4 clustered histone 8, 8365

N. diseases: 122; N. variants: 1
Disease: Refractory cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0677936
Disease: Refractory cancer
Refractory cancer 		0.010 Biomarker phenotype BEFREE Our study results suggest that hMOF and SIRT1 activities are critical parameters in HDACi-mediated sensitization of multidrug-resistant cancer cells to topoisomerase II inhibitor and increased H4K16 acetylation. 20118981 2010