|
Autistic Disorder
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
The present study aimed to investigate whether ZNF533, DOCK4, and IMMP2L genes are also associated with autism in a northeastern Chinese Han population.
|
24599690 |
2014 |
|
Autistic Disorder
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.
|
19401682 |
2010 |
|
Autistic Disorder
|
0.330 |
Biomarker
|
disease |
CTD_human |
High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.
|
19401682 |
2010 |
|
Autistic Disorder
|
0.330 |
Biomarker
|
disease |
BEFREE |
We screened 39 GTS patients, and, due to the localization of IMMP2L in the critical region for the autistic disorder (AD) locus on chromosome 7q (AUTS1), 95 multiplex AD families; however, no coding mutations were found in either GTS or AD patients.
|
17043892 |
2007 |
|
Diffuse Large B-Cell Lymphoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas.
|
27356265 |
2016 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study.
|
31268507 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
|
30285260 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
|
29483656 |
2018 |
|
Child Development Disorders, Pervasive
|
0.100 |
GeneticVariation
|
group |
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.
|
28991256 |
2017 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of schizophrenia in Ashkenazi Jews.
|
26198764 |
2015 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Biological insights from 108 schizophrenia-associated genetic loci.
|
25056061 |
2014 |
|
Gilles de la Tourette syndrome
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
The genetic factors relevant to the development of both disorders are yet to be fully understood, however, some genetic association studies have identified inner mitochondrial membrane peptidase subunit 2 (IMMP2L) as a potential risk gene for both GTS and ASD.
|
31233820 |
2019 |
|
Gilles de la Tourette syndrome
|
0.070 |
Biomarker
|
disease |
BEFREE |
IMMP2L, the gene encoding the inner mitochondrial membrane peptidase subunit 2-like protein, has been reported as a candidate gene for Tourette syndrome, autism spectrum disorder (ASD) and additional neurodevelopmental disorders.
|
29152845 |
2018 |
|
Gilles de la Tourette syndrome
|
0.070 |
Biomarker
|
disease |
BEFREE |
IMMP2L has been implicated in Tourette syndrome, but how its dysfunction contributes to the neurodevelopmental phenotype remains unclear.
|
27932244 |
2017 |
|
Gilles de la Tourette syndrome
|
0.070 |
Biomarker
|
disease |
BEFREE |
The current findings give further evidence for the role of IMMP2L as a susceptibility factor in Tourette syndrome and suggest that intronic changes in disease susceptibility genes should be investigated further for presence of alternatively spliced exons.
|
24549057 |
2014 |
|
Gilles de la Tourette syndrome
|
0.070 |
Biomarker
|
disease |
BEFREE |
The IMMP2L gene has previously been proposed as a candidate gene for Tourette syndrome, and our case provides further evidence of its possible role in the pathogenesis.
|
21386874 |
2011 |
|
Gilles de la Tourette syndrome
|
0.070 |
GeneticVariation
|
disease |
BEFREE |
We screened 39 GTS patients, and, due to the localization of IMMP2L in the critical region for the autistic disorder (AD) locus on chromosome 7q (AUTS1), 95 multiplex AD families; however, no coding mutations were found in either GTS or AD patients.
|
17043892 |
2007 |
|
Gilles de la Tourette syndrome
|
0.070 |
Biomarker
|
disease |
BEFREE |
Disruption of a novel gene (IMMP2L) by a breakpoint in 7q31 associated with Tourette syndrome.
|
11254443 |
2001 |
|
Malignant Neoplasms
|
0.050 |
AlteredExpression
|
group |
BEFREE |
Adult expression of IMP2 is often associated with several types of disease and cancer.
|
29859241 |
2018 |
|
Primary malignant neoplasm
|
0.050 |
AlteredExpression
|
group |
BEFREE |
Adult expression of IMP2 is often associated with several types of disease and cancer.
|
29859241 |
2018 |
|
Malignant Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
IMP2 stabilization of <i>HMGA1</i> mRNA plus IMP2 stimulated IGF2 production synergistically drive cancer cell proliferation and account for IMP2's tumor promoting action.
|
28753127 |
2017 |