SOX14, SRY-box transcription factor 14, 8403

N. diseases: 11; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.020 AlteredExpression disease BEFREE This study advances our understanding about the role of SOX14 and might explain the molecular mechanism by which this transcription factor could exert tumor suppressor properties in cervical carcinoma. 28926586 2017
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.020 Biomarker disease BEFREE SOX1 and SOX14 are methylation biomarkers applicable for screening of all cervical cancer types. 27738327 2016
CUI: C0221060
Disease: Mobius Syndrome
Mobius Syndrome 		0.020 GeneticVariation disease BEFREE Human SOX14 is localised to a 1.15-Mb yeast artificial chromosome on chromosome 3q23, close to loci for BPES (blepharophimosis, ptosis, epicanthus inversus syndrome) and Mobius syndrome. 10798354 2000
CUI: C0221060
Disease: Mobius Syndrome
Mobius Syndrome 		0.020 Biomarker disease BEFREE This location places SOX14 within a chromosome interval associated with two distinct syndromes that affect craniofacial development: Blepharophimosis-ptosis-epicantus inversus syndrome and Möbius syndrome. 9925951 1998
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.010 Biomarker group BEFREE Recently, it became evident that SOX14 is one of four hypermethylated genes in cervical carcinoma, considered as a tumor suppressor candidate in this type of malignancy. 28926586 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.010 AlteredExpression group BEFREE This study advances our understanding about the role of SOX14 and might explain the molecular mechanism by which this transcription factor could exert tumor suppressor properties in cervical carcinoma. 28926586 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.010 Biomarker group BEFREE Recently, it became evident that SOX14 is one of four hypermethylated genes in cervical carcinoma, considered as a tumor suppressor candidate in this type of malignancy. 28926586 2017
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.010 Biomarker disease BEFREE SOX1 and SOX14 are methylation biomarkers applicable for screening of all cervical cancer types. 27738327 2016
CUI: C0279672
Disease: Cervical Adenocarcinoma
Cervical Adenocarcinoma 		0.010 Biomarker disease BEFREE Four markers (SLC6A5, SOX1, SOX14 and TBX20) detected ADC and SCC with similar sensitivity. 27738327 2016
CUI: C4048328
Disease: cervical cancer
cervical cancer 		0.010 Biomarker disease BEFREE SOX1 and SOX14 are methylation biomarkers applicable for screening of all cervical cancer types. 27738327 2016
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.010 Biomarker disease BEFREE A set of seven potential markers (LRRN1, PRICKLE2, VHL, BHLHE40, RBSP3, CGGBP1 and SOX14) is promising for discrimination of ADC and SCC. 23478628 2013
CUI: C0005744
Disease: Blepharophimosis
Blepharophimosis 		0.010 Biomarker disease BEFREE Human SOX14 is localised to a 1.15-Mb yeast artificial chromosome on chromosome 3q23, close to loci for BPES (blepharophimosis, ptosis, epicanthus inversus syndrome) and Mobius syndrome. 10798354 2000
CUI: C0740404
Disease: Limb defects
Limb defects 		0.010 Biomarker group BEFREE SOX14 is a candidate gene for limb defects associated with BPES and Möbius syndrome. 10798354 2000