CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Disease: Malignant neoplasm of urinary bladder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005684
Disease: Malignant neoplasm of urinary bladder
Malignant neoplasm of urinary bladder 		0.040 GeneticVariation disease BEFREE Caspase-8 rs3834129 genotypes play a minor role in the personal susceptibility to bladder cancer in Taiwan. 31519577 2019
CUI: C0005684
Disease: Malignant neoplasm of urinary bladder
Malignant neoplasm of urinary bladder 		0.040 Biomarker disease BEFREE Of the patients, 19.4% for Casp-8 and 28.2% for Rb1 showed methylation in bladder cancer. 19160091 2009
CUI: C0005684
Disease: Malignant neoplasm of urinary bladder
Malignant neoplasm of urinary bladder 		0.040 GeneticVariation disease BEFREE These results suggested that the CASP8 -652 6N ins/del polymorphism is involved in etiology of bladder cancer and thus may be a marker for genetic susceptibility to bladder cancer in Chinese populations. 19276244 2009
CUI: C0005684
Disease: Malignant neoplasm of urinary bladder
Malignant neoplasm of urinary bladder 		0.040 GeneticVariation disease BEFREE We undertook a case-control study of 212 (BC) cases and 250 controls to investigate the association between Caspase 9-1263A > G, Caspase 9-293del, and Caspase 8-6 N ins/del polymorphism and BC susceptibility by polymerase chain reaction (PCR) restriction fragment length polymorphism (RFLP) method, and further to study the influence on recurrence in patients after Bacillus Calmette-Guerin (BCG) immunotherapy. 19412632 2009