Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.040 Biomarker disease BEFREE In particular, SHP can be strongly reduced upon stimulation, such as by HCV infection. 31400386 2019
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.040 Biomarker disease BEFREE SHP1 silencing (siSHP1) reversed the pro-oncogenic effects of HCV infection, inducing a significant decrease in liver lipid accumulation and in NS5A protein expression. 27661118 2016
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.040 AlteredExpression disease BEFREE Pharmacological AMPK activation recovered SHP expression, and Ad-SHP inhibited HCV-induced fibrotic gene expression. 25976932 2015
CUI: C0019196
Disease: Hepatitis C
Hepatitis C
0.040 AlteredExpression disease BEFREE HCV infection increased the expression of nuclear receptors small heterodimer partner and constitutive androstane receptor (CAR) as well as genes involved in fatty acid trafficking, bile acid synthesis and uptake, and inflammatory response. 21898497 2011