Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.100 Biomarker group BEFREE To explore the anti-tumor effects of esophageal cancer-related gene 2 (ECRG2) in combination with cisplatin (DDP) in DDP-resistant esophageal cancer cells (EC9706/DDP). 28348485 2017
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma
0.100 Biomarker disease BEFREE To explore the anti-tumor effects of esophageal cancer-related gene 2 (ECRG2) in combination with cisplatin (DDP) in DDP-resistant esophageal cancer cells (EC9706/DDP). 28348485 2017
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.100 Biomarker disease BEFREE These findings suggest that the combination of ECRG2 and DDP may be a promising strategy for the clinical treatment of esophageal cancers that are resistant to DDP. 28348485 2017
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.100 Biomarker group BEFREE Expression of bcl-2 and p53 in induction of esophageal cancer cell apoptosis by ECRG2 in combination with cisplatin. 24606472 2014
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma
0.100 Biomarker disease BEFREE Expression of bcl-2 and p53 in induction of esophageal cancer cell apoptosis by ECRG2 in combination with cisplatin. 24606472 2014
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.100 Biomarker disease BEFREE Expression of bcl-2 and p53 in induction of esophageal cancer cell apoptosis by ECRG2 in combination with cisplatin. 24606472 2014
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.100 Biomarker group BEFREE A short tandem repeat (STR) polymorphism in the 3'UTR region of esophageal cancer-related gene 2 (ECRG2, also known as SPINK7) has been widely reported to be associated with the incidence and the prognosis of esophageal squamous cell carcinoma (ESCC). 22315007 2013
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma
0.100 Biomarker disease BEFREE A short tandem repeat (STR) polymorphism in the 3'UTR region of esophageal cancer-related gene 2 (ECRG2, also known as SPINK7) has been widely reported to be associated with the incidence and the prognosis of esophageal squamous cell carcinoma (ESCC). 22315007 2013
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.100 Biomarker disease BEFREE A short tandem repeat (STR) polymorphism in the 3'UTR region of esophageal cancer-related gene 2 (ECRG2, also known as SPINK7) has been widely reported to be associated with the incidence and the prognosis of esophageal squamous cell carcinoma (ESCC). 22315007 2013
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.100 Biomarker group BEFREE Esophageal cancer-related gene 2 (ECRG2) is found to be critical in the process of carcinogenesis. 23079671 2012
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma
0.100 Biomarker disease BEFREE Esophageal cancer-related gene 2 (ECRG2) is found to be critical in the process of carcinogenesis. 23079671 2012
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.100 Biomarker disease BEFREE Esophageal cancer-related gene 2 (ECRG2) is found to be critical in the process of carcinogenesis. 23079671 2012
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.100 AlteredExpression group BEFREE However, ECRG2 gene was significantly down-regulated in primary esophageal cancer tissues. 21042721 2010
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma
0.100 AlteredExpression disease BEFREE However, ECRG2 gene was significantly down-regulated in primary esophageal cancer tissues. 21042721 2010
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.100 AlteredExpression disease BEFREE However, ECRG2 gene was significantly down-regulated in primary esophageal cancer tissues. 21042721 2010
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.100 GeneticVariation group BEFREE Short tandem repeat (STR) polymorphisms in exon 4 of esophageal cancer related gene 2 (ECRG2) are a prognostic marker for squamous cell carcinoma (SCC) of the esophagus. 17418617 2008
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma
0.100 GeneticVariation disease BEFREE Short tandem repeat (STR) polymorphisms in exon 4 of esophageal cancer related gene 2 (ECRG2) are a prognostic marker for squamous cell carcinoma (SCC) of the esophagus. 17418617 2008
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma
0.100 GeneticVariation disease BEFREE In conclusion, the ECRG2 TCA (3)/TCA (4) genotype is associated with the risk of oesophageal carcinoma in a North Indian population. 18618216 2008
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.100 GeneticVariation disease BEFREE In the present study, ECRG2 STR polymorphism was studied in 134 patients with oesophageal cancer and 194 controls, using PCR and polyacrylamide gel electrophoresis. 18618216 2008
CUI: C0546837
Disease: Malignant neoplasm of esophagus
Malignant neoplasm of esophagus
0.100 GeneticVariation disease BEFREE Short tandem repeat (STR) polymorphisms in exon 4 of esophageal cancer related gene 2 (ECRG2) are a prognostic marker for squamous cell carcinoma (SCC) of the esophagus. 17418617 2008
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.100 Biomarker group BEFREE The esophageal cancer-related gene 2 (ECRG2) is a novel gene that shows sequence similarity to KAZAL-type serine protease inhibitor. 17602171 2007
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.100 GeneticVariation group BEFREE Genetically fixed STR polymorphism TCA3/TCA3 in exon 4 of ECRG2 is associated with poor clinical outcome in surgically treated esophageal cancer patients and might be a potential prognostic marker. 17693286 2007
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.100 GeneticVariation group BEFREE Short tandem repeat (STR) polymorphisms in exon 4 of the Kazal-type esophageal cancer related gene (ECRG2) have been reported to be associated with esophageal carcinoma. 17352218 2007
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.100 GeneticVariation group LHGDN Genetically fixed STR polymorphism TCA3/TCA3 in exon 4 of ECRG2 is associated with poor clinical outcome in surgically treated esophageal cancer patients and might be a potential prognostic marker. 17693286 2007
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma
0.100 GeneticVariation disease BEFREE Short tandem repeat (STR) polymorphisms in exon 4 of the Kazal-type esophageal cancer related gene (ECRG2) have been reported to be associated with esophageal carcinoma. 17352218 2007