SPZ1, spermatogenic leucine zipper 1, 84654

N. diseases: 173; N. variants: 0
Disease: keratoacanthoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022572
Disease: keratoacanthoma
keratoacanthoma 		0.010 AlteredExpression disease BEFREE By comparing the expression of p53, cyclin D1, p16, hTERT, and TSP-1 in spontaneously regressing keratoacanthoma (KA) as a paradigm of early neoplasia, with malignant invasive cutaneous squamous cell carcinoma (SCC) as a paradigm of advanced tumour development, we are now able to assign the changes in the expression of these proteins to specific stages and allocate them to defined roles in the multi-step process of skin carcinogenesis. 17198740 2007