RAE1, ribonucleic acid export 1, 8480

N. diseases: 23; N. variants: 0
Disease: Solid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.010 Biomarker phenotype BEFREE However, no effective <i>in vivo</i> approaches are available to restore these ligands across different types of solid tumors because the classic stress signal-dependent induction of this ligand <i>in vitro</i> is transient and has rarely been duplicated in solid tumors <i>in vivo</i> We found that coadministration of an immune stimulatory signal (IL12) and chemotherapy (doxorubicin) restored the NKG2D ligand Rae-1 in multiple tumor types, including a human tumor model. 28223282 2017