Disease: IMMUNE SUPPRESSION ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1840264
Disease: IMMUNE SUPPRESSION
IMMUNE SUPPRESSION 		0.040 Biomarker phenotype BEFREE Tim-3-gal-9 interaction is a primary mechanism promoting immune suppression. 30231785 2020
CUI: C1840264
Disease: IMMUNE SUPPRESSION
IMMUNE SUPPRESSION 		0.040 Biomarker phenotype BEFREE Their protective roles can be enhanced when co-administration, because DEX may relieve the Galectin-9/Tim-3 axis-mediated immune suppression. 31631367 2020
CUI: C1840264
Disease: IMMUNE SUPPRESSION
IMMUNE SUPPRESSION 		0.040 AlteredExpression phenotype BEFREE In addition, α-lactose, a blocker for the interaction of Tim-3 and galectin-9, also decreased the autophagy level and immune suppression. 30680089 2019
CUI: C1840264
Disease: IMMUNE SUPPRESSION
IMMUNE SUPPRESSION 		0.040 AlteredExpression phenotype BEFREE Together, these results suggested that in osteosarcoma patients, Tim3 expression did not directly mediate immune suppression, but the interaction between Tim3<sup>+</sup> T cells and monocytes, naive CD4<sup>+</sup> T cells, and Gal9-expressing CD4<sup>+</sup>CD25<sup>+</sup> Tregs could resulting in progressive suppression of Th1 responses. 28103502 2017