Disease: Adult Medulloblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.050 Biomarker disease BEFREE WIP1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma. 27086929 2016
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.050 Biomarker disease BEFREE WIP1 knockdown also improved the survival of mice xenografted with WIP1 high-expressing medulloblastoma cells. 24632620 2015
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.050 AlteredExpression disease BEFREE Nutlin-3a does not affect growth of medulloblastoma cells with stable expression of an empty vector or of mutant WIP1. 22379189 2012
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.050 Biomarker disease BEFREE We speculate that suppression of p53 function by combined WIP1-mediated dephosphorylation and SIRT1 deacetylation enables medulloblastoma cell survival but p53-dependent and independent apoptotic pathways remain intact. 19907922 2010
CUI: C0278876
Disease: Adult Medulloblastoma
Adult Medulloblastoma 		0.050 Biomarker disease BEFREE We examined primary medulloblastoma specimens and cell lines, and detected WIP1 copy gain and amplification prevalent among but not exclusively in the tumors with 17q gain and isochromosome 17q (i17q), which are among the most common cytogenetic lesions in medulloblastoma. 17932621 2008