RUNX2, RUNX family transcription factor 2, 860

N. diseases: 405; N. variants: 37
Disease: Progression of prostate cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1739135
Disease: Progression of prostate cancer
Progression of prostate cancer 		0.020 AlteredExpression disease BEFREE This study establishes a contributing mechanism for progression of prostate cancer cells to a more apoptosis-resistant and thus malignant phenotype, whereby increased expression of RUNX2 modulates the expression of apoptosis-associated factors, specifically Bcl-2. 23073173 2012
CUI: C1739135
Disease: Progression of prostate cancer
Progression of prostate cancer 		0.020 Biomarker disease BEFREE Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions. 19915614 2010