RDH16, retinol dehydrogenase 16, 8608

N. diseases: 4; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.010 Biomarker group BEFREE Clinical significance and function of RDH16 as a tumor-suppressing gene in hepatocellular carcinoma. 31661588 2020
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.010 AlteredExpression disease BEFREE Downregulation of RDH16 has been detected in approximately 90% of primary HCCs, which was significantly associated with high serum alpha-fetoprotein level, tumor size, microsatellite formation, thrombus, and poor overall survival of HCC patients. 31661588 2020
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.010 Biomarker disease BEFREE NSPc1 promotes cancer stem cell self-renewal by repressing the synthesis of all-trans retinoic acid via targeting RDH16 in malignant glioma. 28394339 2017
CUI: C0014170
Disease: Endometrial Neoplasms
Endometrial Neoplasms 		0.010 Biomarker group LHGDN Expression of a retinol dehydrogenase (hRoDH-4), a member of the retinol/steroid dehydrogenase family implicated in retinoic acid biosynthesis, in normal and neoplastic endometria. 11967490 2002