SERPINA6, serpin family A member 6, 866

N. diseases: 68; N. variants: 4
Disease: Pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030193
Disease: Pain
Pain 		0.030 Biomarker phenotype BEFREE Naturally occurring human mutations influence a wide range of CBG properties and point toward a role in hitherto unexplained chronic musculoskeletal pain and fatigue disorders as well as potentially affecting fertility outcomes including offspring gender. 27214312 2016
CUI: C0030193
Disease: Pain
Pain 		0.030 Biomarker phenotype BEFREE A single effect was also identified in SERPINA6 but was no longer significant when adjusted for pain. 20403506 2010
CUI: C0030193
Disease: Pain
Pain 		0.030 GeneticVariation phenotype BEFREE Multiple SNPs in SERPINA6 were associated with the maximum number of pain sites; for example, each copy of the T allele of rs941601 was associated with having 16% (proportional change=1.16, 95% CI 1.04 to 1.28, p=0.006) more pain sites compared to participants with the CC genotype. 19723618 2010