BECN1, beclin 1, 8678

N. diseases: 373; N. variants: 2
Disease: Diabetes Mellitus, Non-Insulin-Dependent ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.240 AlteredExpression disease BEFREE SS-31 also led to a drop in <i>BECN1</i> gene expression, and Beclin1 and LC3 II/I protein expression in T2D patients. 31466264 2019
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.240 AlteredExpression disease BEFREE Reduced transcription of BECN1 and LAMP2 and unchanged expression of MAP1LC3B and ATG5 were observed in PBMCs of T2D patients. 29654511 2018
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.240 Biomarker disease BEFREE Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway. 26386349 2016
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.240 AlteredExpression disease BEFREE Both the number of autophagosomes and Beclin1 expression were increased in EPC from patients with DM. 24750349 2014
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.240 Therapeutic disease RGD Enhanced autophagy plays a cardinal role in mitochondrial dysfunction in type 2 diabetic Goto-Kakizaki (GK) rats: ameliorating effects of (-)-epigallocatechin-3-gallate. 21820301 2012