URI1, URI1 prefoldin like chaperone, 8725

N. diseases: 53; N. variants: 0
Disease: Malignant neoplasm of ovary ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.310 AlteredExpression disease BEFREE Unconventional prefoldin RPB5 interactor (URI, or RMP, a member of the prefoldin family of molecular chaperones) exhibits oncogenic activity in several types of cancer, including ovarian cancer. 30662936 2019
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary 		0.310 Biomarker disease CTD_human URI is an "addicting" oncogene selectively required for the survival of ovarian cancer cells with increased URI copy number. 21397856 2011