ADAM7, ADAM metallopeptidase domain 7, 8756

N. diseases: 5; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1321872
Disease: Stage IV Skin Melanoma
Stage IV Skin Melanoma 		0.300 GeneticVariation disease UNIPROT
CUI: C0024266
Disease: Lymphocytic Choriomeningitis
Lymphocytic Choriomeningitis 		0.010 Biomarker disease BEFREE Combined vaccination with rLCMV-vectored GPCMV gB(dCt) and pp65 (GP83) conferred better protection against maternal viremia than subunit or either monovalent rLCMV vaccine. 27795301 2017
CUI: C0153014
Disease: Non-arthropod borne lymphocytic choriomeningitis
Non-arthropod borne lymphocytic choriomeningitis 		0.010 Biomarker disease BEFREE Combined vaccination with rLCMV-vectored GPCMV gB(dCt) and pp65 (GP83) conferred better protection against maternal viremia than subunit or either monovalent rLCMV vaccine. 27795301 2017
CUI: C0041234
Disease: Chagas Disease
Chagas Disease 		0.010 Biomarker disease BEFREE Taken together, these novel results show that the recombinant Ad5 presenting T. cruzi gp83 antigen is a useful candidate for the development of a vaccine against Chagas disease. 25144771 2014
CUI: C0242723
Disease: Parasitemia
Parasitemia 		0.010 Biomarker disease BEFREE Our findings indicate that mice immunized with the vector Ad5-gp83 and challenged with a lethal dose of T. cruzi trypomastigotes confer strong immunoprotection with significant reduction in parasitemia levels, increased survival rate and induction of neutralizing antibodies. 25144771 2014