Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections
0.030 Biomarker group BEFREE Furthermore, the expression of zebrafish histone H2A was decreased by RIP2 deficiency with and/or without bacterial infection. 31336107 2019
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections
0.030 AlteredExpression group BEFREE The results showed that NOD1 can identify LPS and activate the NF-κB signal pathway by recruiting RIPK2 and then promoting the expression of inflammatory cytokines to induce the resistance of organism against bacterial infection. 30013548 2018
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections
0.030 Biomarker group BEFREE Collectively, these findings demonstrate that NOD1 detects PG within early endosomes, thereby promoting RIP2-dependent autophagy and inflammatory signaling in response to bacterial infection. 24746552 2014