CES2, carboxylesterase 2, 8824

N. diseases: 87; N. variants: 1
Disease: Fatty Liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.020 Biomarker disease BEFREE In mice, obesity reduced CES2, whereas adenoviral delivery of human CES2 reversed hepatic steatosis, improved glucose tolerance, and decreased inflammation. 28099843 2017
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.020 AlteredExpression disease BEFREE Restoration of hepatic CES2 expression in db/db or HFD-fed mice markedly ameliorates liver steatosis and insulin resistance. 26806650 2016