Disease: Liver neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.050 Biomarker group BEFREE The information presented in this study suggests that cis-bifenthrin (cis-BF) could activate pregnane X receptor (PXR) mediated pathway and lead to the lipid accumulation of human hepatoma (HepG2) cells. 29554630 2018
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.050 Biomarker group BEFREE These results suggest that in mice imazalil activates PXR to enhance hepatocyte proliferation mediated by CAR-activating liver tumor promoters. 29973476 2018
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.050 Biomarker group BEFREE However, these results could not rule out a role for the pregnane X receptor (PXR) in liver tumor formation. 28218408 2017
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.050 Biomarker group BEFREE The signaling pathways downstream of PAR-2 activation that lead to hepatoma cell proliferation were analyzed. 22940775 2012
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.050 AlteredExpression group BEFREE Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174T cells. 22363234 2012