CCKBR, cholecystokinin B receptor, 887

N. diseases: 105; N. variants: 4
Disease: Carcinoid Tumor ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007095
Disease: Carcinoid Tumor
Carcinoid Tumor 		0.020 Biomarker phenotype BEFREE The role of CCK2R in physiological (atrophic gastritis, pernicious anemia) and pathological (Zollinger-Ellison syndrome) hypergastrinemic states, its effects on the gastric mucosa (ECL cell hyperplasia, carcinoids, parietal cell mass) and its role in acid-peptic disorders are clearly defined. 17584143 2007
CUI: C0007095
Disease: Carcinoid Tumor
Carcinoid Tumor 		0.020 AlteredExpression phenotype BEFREE Thus CCK-B/gastrin receptor blockade of hypergastrinemic animals reduces the HDC mRNA expression in normal mucosa but not in ECL cell carcinoids. 10651065 1999