CCKBR, cholecystokinin B receptor, 887

N. diseases: 105; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 AlteredExpression disease BEFREE CCKBR/GR expression was significantly high in well and moderately differentiated SC samples as compared to poorly differentiated samples. 27072272 2016
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 AlteredExpression disease BEFREE Construct a new immunotoxin (IT) targeting of CCK2R overexpressed gastric cancer. 23311704 2013
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 AlteredExpression disease BEFREE The protein level of cholecystokinin B receptor, which might be the target gene of miR-148a and miR-152, was analyzed by Western blot in 40 patients with gastric cancer. 20422307 2010
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 Biomarker disease BEFREE Overexpression of IGF-1/IGF-1R and gastrin/CCK-BR promotes the disorderly proliferation of gastric mucosa epithelia and it is of great significance in the carcinogenesis and development of gastric carcinoma. 15929170 2005
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 Biomarker disease BEFREE Gastrin/CCK-B receptor autocrine or paracrine pathway may possibly play an important role in the progression of gastric cancer. 15040018 2004
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 Biomarker disease BEFREE Characterization of CCK-B/gastrin-like receptors in human gastric carcinoma. 9458369 1998
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.070 AlteredExpression disease BEFREE The CCK-B receptor mRNA expression was detectable in only 1/14 (7%) samples of gastric cancer, although it was detectable in 10/12 (83%) body mucosa of the stomach. 8844981 1996