KRIT1, KRIT1 ankyrin repeat containing, 889

N. diseases: 201; N. variants: 43
Disease: Endothelial dysfunction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.020 Biomarker phenotype BEFREE In conclusion, we found that KRIT1 deficiency promotes ED, suggesting that, besides CCM, KRIT1 may be implicated in genetic susceptibility to the development of atherosclerotic lesions. 31590384 2019
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.020 Biomarker phenotype BEFREE Expression level of multiple markers implicated in inflammation (tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-4, IL-6, IL-8, IL-10; metalloproteinase MMP-9) and markers of endothelial dysfunction (I-CAM and V-CAM) was determined from lung tissues mRNA using RT-PCR. 30056108 2018