BCL10, BCL10 immune signaling adaptor, 8915

N. diseases: 205; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.040 Biomarker disease BEFREE In this study, differential protein expression of the major Fas family members (Fas, FasL, and FAP-1) and Bcl-2 family members (Bax, Bcl-2, and Bcl-X(L)) in benign versus malignant surface epithelial ovarian tumors was evaluated at the protein level by immunohistochemistry. 22688594 2012
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.040 AlteredExpression disease LHGDN Erythropoietin treatment of human ovarian cancer cells results in enhanced signaling and a paclitaxel-resistant phenotype. 17893875 2008
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.040 Biomarker disease BEFREE Consequently, therapeutic strategy for treatment of ovarian cancer that target Bcl-X(L) will likely yield variable responses. 16188300 2006
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.040 AlteredExpression disease BEFREE We conclude that overexpression of antiapoptotic proteins Bcl-2 and Bcl-X(L) and down-regulation of caspase-3 activity may be associated with cisplatin resistance in human ovarian cancer. 15156398 2004