DIRAS3, DIRAS family GTPase 3, 9077

N. diseases: 52; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.050 Biomarker group BEFREE Re-expression of ARHI was achieved by transfection, by treatment with trichostatin A (TSA) or by a combination of TSA and 5-aza-2'-deoxycytidine (DAC) in breast cancer cell cultures and by liposomal delivery of ARHI in breast tumor xenografts. 21244707 2011
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.050 AlteredExpression group LHGDN E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer. 16158053 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.050 PosttranslationalModification group LHGDN Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers. 12874023 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.050 AlteredExpression group LHGDN [NOEY2 gene mRNA expression in breast cancer tissue and its relation to clinicopathological parameters]. 12485503 2002
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.050 AlteredExpression group BEFREE ARHI/NOEY2 inactivation may be important in breast tumor pathogenesis. 11914599 2002