CD1A, CD1a molecule, 909

N. diseases: 121; N. variants: 2
Disease: Endocardial Cushion Defects ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014116
Disease: Endocardial Cushion Defects
Endocardial Cushion Defects 		0.040 Biomarker group BEFREE Immunohistochemically, the LCH contained CD1a-positive Langerhans cells and the ECD had CD1a-negative, CD68-positive foamy histiocytes. 26466952 2016
CUI: C0014116
Disease: Endocardial Cushion Defects
Endocardial Cushion Defects 		0.040 Biomarker group BEFREE The diagnosis of ECD was made by characteristic histopathologic features in addition to clinical-radiographic features and the typical immunoprofile (positive for cluster of differentiation 68 [CD68], CD163, and p16; negative for CD1a and S-100). 25454479 2015
CUI: C0014116
Disease: Endocardial Cushion Defects
Endocardial Cushion Defects 		0.040 Biomarker group BEFREE Diagnosis of ECD involves the analysis of histiocytes in tissue biopsies: these are typically foamy and CD68+ CD1a- in ECD, whereas in Langerhans cell histiocytosis (LCH) they are CD68+ CD1a+. 24532298 2014
CUI: C0014116
Disease: Endocardial Cushion Defects
Endocardial Cushion Defects 		0.040 Biomarker group BEFREE Diagnosis of ECD is based on the identification in tissue biopsy of histiocytes, which are typically foamy and immunostain for CD68+ CD1a-. 23597965 2013