ACVR1B, activin A receptor type 1B, 91

N. diseases: 41; N. variants: 6
Disease: Immunologic Deficiency Syndromes ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021051
Disease: Immunologic Deficiency Syndromes
Immunologic Deficiency Syndromes 		0.010 Biomarker group BEFREE These results together suggest that the HA-CD44 and activin-A-ALK4 pathways differentially regulate the spheroid formation and maintenance of ALDH<sup>bright</sup> CICs in MM cells, and that both pathways play critical roles in tumor growth in immunodeficient hosts. 30061637 2018