MTMR4, myotubularin related protein 4, 9110

N. diseases: 7; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0345967
Disease: Malignant mesothelioma
Malignant mesothelioma 		0.300 Biomarker disease CTD_human MicroRNA and mRNA features of malignant pleural mesothelioma and benign asbestos-related pleural effusion. 25756049 2015
CUI: C0026846
Disease: Muscular Atrophy
Muscular Atrophy 		0.200 Biomarker phenotype RGD The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4. 19125695 2009
CUI: C0021704
Disease: Intelligence
Intelligence 		0.100 GeneticVariation phenotype GWASCAT Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. 29844566 2018
CUI: C0523979
Disease: Vitamin D3 measurement
Vitamin D3 measurement 		0.100 GeneticVariation phenotype GWASCAT Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study. 25208829 2014
CUI: C0919758
Disease: Vitamin D measurement
Vitamin D measurement 		0.100 GeneticVariation phenotype GWASCAT Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study. 25208829 2014
CUI: C0019348
Disease: Herpes Simplex Infections
Herpes Simplex Infections 		0.010 Biomarker group BEFREE We established MTMR3 and MTMR4 double knockout (DKO) RAW264.7 macrophage cells and found that they exhibited increased type I interferon production after interferon-stimulatory DNA (ISD) stimulation and herpes simplex virus 1 infection concomitant with enhanced IRF3 phosphorylation. 30944173 2019
CUI: C0340552
Disease: High altitude pulmonary hypertension
High altitude pulmonary hypertension 		0.010 GeneticVariation disease BEFREE We show here evidence of three candidate genes MTMR4, TMOD3 and VCAM1 that are functionally associated with well-known molecular and pathophysiological processes and which likely lead to HAPH in this population. 30254217 2019