CD1D, CD1d molecule, 912

N. diseases: 140; N. variants: 0
Disease: Psoriasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.030 Biomarker disease BEFREE The in vivo regulation of CD1d has significant implications for the pathologic mechanisms of certain immunologic skin diseases in which NKT cells play a role, such as allergic contact dermatitis and psoriasis. 19592659 2009
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.030 AlteredExpression disease LHGDN These results implied that PKCzeta is an important transduction molecule downstream of TNF-alpha signaling and is associated with increased expression of CD1d that may enhance CD1d-NKT cell interactions in psoriasis lesions. 18385757 2008
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.030 AlteredExpression disease BEFREE We conclude that CD1d can be expressed in a functionally active form by keratinocytes and is up-regulated in psoriasis and other inflammatory dermatoses. 11034419 2000