CD2, CD2 molecule, 914

N. diseases: 50; N. variants: 2
Disease: Sjogren's Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.010 Biomarker disease BEFREE We reported previously that T cells specific RORγt-transgenic-mice under human CD2 promoter (RORγt-Tg mice) developed severe spontaneous Sjögren's syndrome (SS)-like sialadenitis, induced by RORγt-overexpressing CD4<sup>+</sup> T cells and reduced regulatory T cells. 31837283 2019