CD3E, CD3e molecule, 916

N. diseases: 73; N. variants: 4
Disease: Graft-vs-Host Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018133
Disease: Graft-vs-Host Disease
Graft-vs-Host Disease 		0.020 Biomarker disease BEFREE In immunodeficient mice, anti-CD3ε PEBL-T cells had markedly reduced GVHD potential; when transduced with anti-CD19 CAR, these T cells killed engrafted leukemic cells. 29507075 2018
CUI: C0018133
Disease: Graft-vs-Host Disease
Graft-vs-Host Disease 		0.020 Biomarker disease BEFREE Anti-CD3 epsilon F(ab')2 prevents graft-versus-host disease by selectively depleting donor T cells activated by recipient alloantigens. 11313428 2001