CD3E, CD3e molecule, 916

N. diseases: 73; N. variants: 4
Disease: Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 Biomarker group BEFREE We also investigated the therapeutic efficacy of these BsAbs in two mouse models: immunodeficient mice xenografted with patient-derived GD2<sup>+</sup> neuroblastoma or HER2<sup>+</sup> breast cancer, and human CD3ε transgenic mice implanted with a GD2<sup>+</sup> murine tumor. 31615814 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 Biomarker group BEFREE The anti-CD3ε antibody UCHT1 enhanced the <i>in vitro</i> tumor killing activity of human γδ T cells by an unknown molecular mechanism. 30038626 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.030 Biomarker group BEFREE Immunocytometry studies (dual staining for CD3 epsilon and TfR) demonstrated that autologous T cells from the peripheral blood but not from the tumor expressed TfR following stimulation with IL2, anti-CD3 or PHA. 8050820 1994