Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.010 Biomarker disease BEFREE Accordingly, molecules involved in necroptotic signaling, such as receptor-interacting serine/threonine-protein kinase 3 (<i>RIPK3</i>) and mixed lineage kinase-like (<i>MLKL</i>) have been found to stimulate anticancer immune responses in mouse models of chemotherapy. mRNAs encoding prominent pro-necrotic gene products (<i>RIPK1</i>, <i>RIPK3</i>, <i>MLKL</i>, <i>PGAM5</i> and <i>DFNA5</i>) were correlated with immune-related metagenes in several cancer types (breast, colorectal, lung, ovary, melanoma), revealing the strongest associations in breast cancer. 28507808 2017