Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Associations of schizophrenia risk genes ZNF804A and CACNA1C with schizotypy and modulation of attention in healthy subjects.
|
31076262 |
2019 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
|
30285260 |
2019 |
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
These findings suggest that ZNF804A affects the resting-state functional activation by interacting with COMT, and may improve our understanding of the neurobiological effects of ZNF804A and its association with schizophrenia.
|
30852803 |
2019 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Previous studies indicated that single-nucleotide polymorphism (SNP) rs1344706 in ZNF804A was strongly associated with schizophrenia and might influence social interaction.
|
31122238 |
2019 |
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Candidates supported by both FTND and TTFC (CHRNA4, THSD7B, RBFOX1, and ZNF804A) were associated with addiction to alcohol, cocaine, and heroin, and were associated with autism and schizophrenia.
|
31294817 |
2019 |
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Our results support evidence implicating CACNA1C and ZNF804A in BD and SCZ, adding novel imaging evidence in clinical populations, and of epistasis-which needs further replication.
|
30079586 |
2019 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression.
|
30626913 |
2019 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Most of the evidence has been provided for the zinc finger protein 804A (ZNF804A) gene, which has been suggested to be implicated in schizophrenia and bipolar disorder.
|
31464994 |
2019 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Differentially spliced genes in ZNF804A-depleted cells were also enriched for genes harboring de novo loss of function mutations in autism spectrum disorder (P = 6.25 × 10-7, enrichment 2.16) and common variant alleles associated with schizophrenia (P = .014), bipolar disorder and schizophrenia (P = .003), and autism spectrum disorder (P = .005).
|
30597088 |
2019 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study.
|
31268507 |
2019 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
|
29121268 |
2018 |
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
These findings suggest that ZNF804A affects the GMV of the prefrontal cortex by interacting with COMT, which may improve our understanding of neurobiological effect of ZNF804A and its association with schizophrenia.
|
28078547 |
2018 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
We showed that ATXN1 was the only direct PPI partner of the know SCZ risk gene ZNF804A, and it also had direct PPIs with other 18 known SCZ risk genes.
|
29055568 |
2018 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The current findings identified the neural impact of the ZNF804A rs1344706 on hippocampal-prefrontal RSFC associated with schizophrenia.
|
29611035 |
2018 |
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment.
|
28924186 |
2018 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, the common variant rs12476147 and the related haplotype block in ZNF804A were associated significantly with schizophrenia in the Han Chinese population.
|
29112096 |
2018 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
|
29483656 |
2018 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Contrary to some - but not all - previous findings, this study of a large sample of schizophrenia cases and healthy controls reveals no evidence for association between grey matter alterations and variation in rs1344706 (ZNF804A).
|
29247760 |
2018 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.
|
28991256 |
2017 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Association between the zinc finger protein 804A (ZNF804A) gene and the risk of schizophrenia and bipolar I disorder across diagnostic boundaries.
|
28544350 |
2017 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The schizophrenia susceptibility gene ZNF804A confers risk of major mood disorders.
|
27784192 |
2017 |
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Genetic association of rs1344706 in ZNF804A with bipolar disorder and schizophrenia susceptibility in Chinese populations.
|
28120939 |
2017 |
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Moreover, a female-specific association has been observed between ZNF804A and schizophrenia.
|
28931092 |
2017 |
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Variation in the gene encoding zinc finger binding protein 804A (ZNF804A) is associated with schizophrenia and bipolar disorder.
|
27837918 |
2017 |