HTR3B, 5-hydroxytryptamine receptor 3B, 9177

N. diseases: 49; N. variants: 10
Disease: Nicotine Dependence ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028043
Disease: Nicotine Dependence
Nicotine Dependence 		0.030 PosttranslationalModification disease BEFREE We further showed these SNPs contribute to ND through four methylated sites in HTR3B. 30405098 2018
CUI: C0028043
Disease: Nicotine Dependence
Nicotine Dependence 		0.030 Biomarker disease BEFREE Previous studies have implicated genes encoding the 5-HT3AB receptors (HTR3A and HTR3B) and the serotonin transporter (SLC6A4), both independently and interactively, in alcohol (AD), cocaine (CD), and nicotine dependence (ND). 24590108 2014
CUI: C0028043
Disease: Nicotine Dependence
Nicotine Dependence 		0.030 Biomarker disease BEFREE We conclude that SLC6A4, HTR3A and HTR3B play a significant role in ND through genetic interactions. 23290502 2013