Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of urinary bladder
0.020 AlteredExpression disease BEFREE These findings suggest that the high expression of ALKBH8 is critical for the growth and progression of bladder cancer. 27329810 2016
Malignant neoplasm of urinary bladder
0.020 Biomarker disease BEFREE In examining the role and function of ALKBH8 in human bladder cancer development in vitro, we found that silencing of ALKBH8 through small interfering RNA transfection reduced reactive oxygen species (ROS) production via down-regulation of NAD(P)H oxidase-1 (NOX-1) and induced apoptosis through subsequent activation of c-jun NH(2)-terminal kinase (JNK) and p38. 19293182 2009