|
Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
We conclude that the Leu1 and Leu2 genes are strong candidates as tumor suppressor gene(s) involved in B-CLL leukemogenesis.
|
9395242 |
1997 |
|
Malignant Neoplasms
|
0.030 |
AlteredExpression
|
group |
BEFREE |
We determined that the transcription of the CD5 gene in T cell malignancies, CLL, SLL and a selected group of EBV transformed lines was identical.
|
1721931 |
1991 |
|
Malignant Neoplasms
|
0.030 |
AlteredExpression
|
group |
BEFREE |
The CD5 gene expression was in all cases identical to that of T-cell malignancies.
|
1690580 |
1990 |
|
B-Cell Lymphomas
|
0.020 |
AlteredExpression
|
group |
LHGDN |
De novo CD5+ diffuse large B-cell lymphoma: results of a detailed clinicopathological review in 120 patients.
|
18556402 |
2008 |
|
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
|
0.020 |
Biomarker
|
disease |
LHGDN |
CD5-undetected by immunohistochemistry, t(11;14)(q13;q32)-positive conjunctival mantle cell lymphoma: a case report.
|
18572329 |
2008 |
|
B-Cell Lymphomas
|
0.020 |
Biomarker
|
group |
LHGDN |
CD5-positive diffuse large B-cell lymphoma with an unusual phenotype: Cytoplasmic CD20 (+), surface CD20 (-).
|
16923582 |
2006 |
|
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
|
0.020 |
GeneticVariation
|
disease |
LHGDN |
We studied the presence of MSI in the CD5 promoter in 134 cases of B-cell chronic lymphocytic leukemia (B-CLL) and 47 of mantle cell lymphoma (MCL) by comparing the pattern of microsatellite repeats on autologous germline and tumor DNA samples.
|
15981803 |
2005 |
|
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Polymorphism in the CD5 gene promoter in B-cell chronic lymphocytic leukemia and mantle cell lymphoma.
|
15981803 |
2005 |
|
Lymphoma
|
0.020 |
Biomarker
|
group |
LHGDN |
Analysis of chromosomal imbalances in de novo CD5-positive diffuse large-B-cell lymphoma detected by comparative genomic hybridization.
|
14603444 |
2004 |
|
Lymphoma
|
0.020 |
GeneticVariation
|
group |
LHGDN |
Genomic instability at the human CD5 gene promoter.
|
11869933 |
2002 |
|
Leukemia, B-Cell
|
0.020 |
GeneticVariation
|
disease |
LHGDN |
Genomic instability at the human CD5 gene promoter.
|
11869933 |
2002 |
|
Leukemia, B-Cell
|
0.020 |
GeneticVariation
|
disease |
LHGDN |
CD5-negative, CD10-negative small B-cell leukemia: variant of chronic lymphocytic leukemia or a distinct entity?
|
12447961 |
2002 |
|
Childhood Leukemia
|
0.020 |
Biomarker
|
disease |
BEFREE |
We have recently identified a minimally deleted region encompassing parts of two adjacent genes, termed LEU1 and LEU2 (leukemia-associated genes 1 and 2), and several additional transcripts.
|
11161783 |
2000 |
|
Childhood Leukemia
|
0.020 |
Biomarker
|
disease |
BEFREE |
Two adjacent genes, termed Leu1 and Leu2 (leukemia-associated gene 1 and 2), were mapped to the minimally deleted region, with several patients showing deletion borders within these genes.
|
9395242 |
1997 |
|
Small Lymphocytic Lymphoma
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Malignant CD5 B cells obtained from patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) were analyzed for immunoglobulin variable gene usage, CD5 gene expression and autoantibody production.
|
1721931 |
1991 |
|
Small Lymphocytic Lymphoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Recently, we found that the G6 CRI also is expressed frequently by neoplastic CD5 (Leu1) B cells from patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma.
|
2503826 |
1989 |
|
Diffuse Large B-Cell Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
<b>Aims:</b> To investigate prognostic values of GCB/non-GCB sub-categorization, Double Protein Expression Lymphoma (DPL), Triple Protein Expression Lymphoma (TPL), positivity of CD5 protein and EBER in patients with DLBCL disease.
|
31171907 |
2019 |
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Lack of expression of sCD5 on T-ALL blasts was correlated closely with predominant transcription of exon E1B and significant loss of exon E1A of the CD5 gene, which is associated with surface expression of CD5 on lymphocytes.
|
28752543 |
2017 |
|
Hepatitis C
|
0.010 |
Biomarker
|
disease |
BEFREE |
A lymphocyte-specific CD5 molecule was recently identified as essential for infection of T cells with native, patient-derived HCV.
|
23626783 |
2013 |
|
Thymic Squamous Cell Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The primary carcinoma showing thymus-like elements of the thyroid frequently expresses KIT and CD5 proteins; similar to thymic squamous cell carcinoma, the overexpression of KIT does not necessarily indicate a gene mutation in this tumor.
|
21835435 |
2012 |
|
Lymphoproliferative Disorders
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Despite the low incidence of microsatellite instability (MSI) in lymphoid malignant neoplasms, it has been reported that the CD5 promoter MSI was relatively frequent among B-cell chronic lymphoproliferative disorders.
|
15981803 |
2005 |
|
Mantle cell lymphoma
|
0.010 |
PosttranslationalModification
|
disease |
BEFREE |
We studied the presence of MSI in the CD5 promoter in 134 cases of B-cell chronic lymphocytic leukemia (B-CLL) and 47 of mantle cell lymphoma (MCL) by comparing the pattern of microsatellite repeats on autologous germline and tumor DNA samples.
|
15981803 |
2005 |
|
Mouth Neoplasms
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Multiplexed PCR revealed homozygous deletion of leu1 in one oral cavity tumor.
|
10502719 |
1999 |
|
Hodgkin Disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
Quantitative immunophenotypic analysis of 13 cases revealed a predominance of Leu1 and Leu3 T cells in all subtypes, except in the case of HD lymphocytic-depression (HDLD).
|
8395909 |
1993 |
|
Lymphoma, Non-Hodgkin
|
0.010 |
Biomarker
|
disease |
BEFREE |
Fourteen patients with FSCCL and 1 patient with DSCCL had a phenotype of follicular center cells (FCC) (CALLA+, SIgD-, Leu-1-, Leu-8- and negative ALPase), and 11 patients with FSCCL had bcl-2 gene rearrangements.
|
1643614 |
1992 |